Monday, May 25, 2015

Vitamin Toxicity Symptoms

You can overdose on any vitamin supplement if you take it long enough and in high enough doses. Since only the fat-soluble vitamins---A, D, E and K---are stored in your body in greater-than-needed amounts, they are the ones mostly like to reach toxic levels. Vitamin D has the potential to be more toxic than any other vitamin. Vitamin E toxicity, on the other hand, is uncommon, and when it does occur, it is less serious than toxicity from vitamins A, D and K.

Skin and Hair Changes

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An overdose of the synthetic form of vitamin K used in supplements can cause red blood cells to burst and release their pigment, which will give the skin a yellowish cast. An overdose can also lead to brain damage. You might find vitamin K in multivitamin supplements, but since higher doses can quickly reach toxic levels, single-vitamin supplements are only available with a doctor's prescription.



Early signs of vitamin A toxicity include dry skin, hair, lips and eyes. In severe cases, the skin will start to peel. Though not technically toxic, too much vitamin A in the form of beta carotene can result in carotenodermia, a deep yellow pigmentation of the skin, including the palms of the hands and the soles of the feet. This is one of the few instances of vitamin overdose that can occur from consuming too much of a particular type of food. In this case, because beta carotene is not only a form of vitamin A but also a deep yellow pigment, that pigment can build up in the body if you eat too many carrots or other yellow-orange foods.

Digestive Discomfort

Very high doses of any vitamin, including water-soluble vitamins like niacin and vitamin C that are not stored in the body, are likely to cause some abdominal discomfort. These symptoms can include loss of appetite, nausea, diarrhea, vomiting and general digestive discomfort. 



When gastrointestinal symptoms appear with vitamin D toxicity, they may be the first signs of hypercalcemia, or too much calcium in the blood. One of the primary roles of vitamin D in the body is to facilitate and regulate calcium absorption into the body. When there is an overabundance of vitamin D, too much calcium is absorbed. Hypercalcemia can lead to organ damage.

Other Indications

With most vitamins, headaches, along with irritability, drowsiness and sometimes weakness will follow other signs of toxicity.



Severe vitamin B6 toxicity can result in a condition known as sensory neuropathy, which causes pain and numbness in fingers and toes and sometimes difficulty walking.



Frequent urination is a sign of vitamin D toxicity, and if overdosing continues, kidney stones and eventually kidney failure can occur.



Although it is unlikely, red blood cell breakage is possible with vitamin E toxicity as a result of the vitamin's interference with normal blood clotting activity in the body. There are usually no changes in skin color as with vitamin K, but hemorrhaging can result.

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